COVID-19 INFORMATION What you need to know about the coronavirus if you are living in Japan or planning a visit.
Remdesivir, injected intravenously daily for 10 days, accelerated the recovery of hospitalized patients with COVID-19, a study found Photo: POOL/AFP/File
health

Anti-viral drug remdesivir effective against coronavirus, study finds

10 Comments
By Ulrich Perrey

Anti-viral drug remdesivir cuts recovery times in coronavirus patients, according to the full results of a trial published Friday night, three weeks after America's top infectious diseases expert said the study showed the medication has "clear-cut" benefits.

Complete results from the research, which was carried out by U.S. government agency the National Institute of Allergy and Infectious Diseases (NIAID), were published by leading medical periodical the New England Journal of Medicine.

The United States authorized the emergency use of remdesivir in hospitals on May 1, followed by Japan, while Europe is considering following suit.

The study found that remdesivir, injected intravenously daily for 10 days, accelerated the recovery of hospitalized COVID-19 patients compared to a placebo in clinical tests on just over a thousand patients across 10 countries.

On April 29, NIAID director Anthony Fauci, who has become the U.S. government's trusted face on the coronavirus pandemic, said preliminary evidence indicated remdesivir had a "clear-cut, significant and positive effect in diminishing the time to recovery."

The National Institutes of Health, of which the NIAID is a part, said Friday in a statement online that investigators found "remdesivir was most beneficial for hospitalized patients with severe disease who required supplemental oxygen."

But the authors of the trial wrote that the drug did not prevent all deaths.

"Given high mortality despite the use of remdesivir, it is clear that treatment with an anti-viral drug alone is not likely to be sufficient," they said.

About 7.1 percent of patients given remdesivir in the trial group died within 14 days -- compared with 11.9 percent in the placebo group.

However, the result is just below the statistical reliability threshold, meaning it could be down to chance rather than the capability of the drug.

© 2020 AFP

©2020 GPlusMedia Inc.

10 Comments
Login to comment

The more good news come, the more things will be better.

1 ( +1 / -0 )

The last line says it all.

4 ( +5 / -1 )

What are the side effects ? I remember the issue was lying especially there.

1 ( +1 / -0 )

For a little more detail, https://arstechnica.com/science/2020/05/the-antiviral-remdesivir-shortens-covid-19-recovery-times-study-shows/ though I disagree with the title for the article.

Seems the drug quickens recovery by 3-4 days, even if given 10 days after the first symptoms were seen. People get better in 11 days, not 15. Didn't see any numbers for what percentage of people got better quicker in the link. In the comments, someone said it was 70%.

However, the overall recovery rate after 29 (or 30) days seems to somewhere around 70% for remdesivir patients and about 60% for placebo patients.

Morbidity rates are about the same, statistically. Need a much larger study to see if there is any impact or not on morbidity.

Also, didn't see the cost of a treatment per person. Getting a daily shot isn't exactly fun and paying $200/day isn't ideal for an 11 day treatment schedule.

3 ( +3 / -0 )

Much more expensive than the much decried hydroxychloroquine without much better results. Of course the drug companies want a new designer COVID drug to sell you at a high price with nasty side effects.

-1 ( +1 / -2 )

Much more expensive than the much decried hydroxychloroquine without much better results.

What? Hydorxychoroquine has resulted in a higher death rate among covid sufferers. While this has not decrease the mortality rate, it has decreased the recovery time by four days. This is significant for two reasons:

1) Four days LESS. I've had the flu for four days total, and almost wanted to die. Do you really think that having a virus ravaging your body for four additional days is a similar result? Hydorxycloroquine doesn't reduce the recovery time by this period.

2) 4/15 days is nearly 25%. The whole point of flattening the curve was to give the health care systems breathing room so that they can effectively care for as many people as possible. If you think that a 25% decrease in time per patient isn't going to make it easier for medical staff to deal with, you're entirely clueless.

2 ( +3 / -1 )

On April 29, NIAID director Anthony Fauci, who has become the U.S. government's trusted face on the coronavirus pandemic, said preliminary evidence indicated remdesivir had a "clear-cut, significant and positive effect in diminishing the time to recovery."

That such a corrupt person can be considered the most trusted face is frightening.

-3 ( +0 / -3 )

However, the result is just below the statistical reliability threshold, meaning it could be down to chance rather than the capability of the drug.

In other words, the test was too small for this small margin to make any decisions on.

0 ( +0 / -0 )

That such a corrupt person can be considered the most trusted face is frightening.

Is anyone who ever disagrees with Trump on something classified as corrupt in your book?

1 ( +2 / -1 )

That such a corrupt person can be considered the most trusted face is frightening.

Is anyone who ever disagrees with Trump on something classified as corrupt in your book?

This has nothing to do with Trump. Fauci's corruption started decades ago with HIV, and continues till today. I don't trust anything that guy says or anything he is associated with.

-1 ( +0 / -1 )

Login to leave a comment

Facebook users

Use your Facebook account to login or register with JapanToday. By doing so, you will also receive an email inviting you to receive our news alerts.

Facebook Connect

Login with your JapanToday account

User registration

Articles, Offers & Useful Resources

A mix of what's trending on our other sites