health

Gene editing 'blocks virus transmission' in human cells

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Sure wish they would improve the antiviral mRNA drugs for herpes. There is only one effective one for the eyes but if the virus mutates within the body, the one drug becomes much less effective.

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The report is very interesting and promising but obviously at this point there is no chance for clinical use yet, the interest is still mostly scientific.

This version of the CRISP is closer to the original role of the protein, used to mess with the genome of the virus to interrupt transmission, with the advantage that it acts only on RNA so there is no risk of permanent changes to the patient cells. But what works well in single cells can be challenging for full organisms, the mRNA vaccines for example are effective because even if the RNA is delivered to a limited number of cells that is enough to stimulate the immune system, but this therapy would need to be delivered to most of the infected cells and be active during the whole time the infection is present, that is a much higher hurdle to surpass.

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