Higher-dose naloxone spray for reversing opioid overdoses didn't save more lives, researchers find

Is there any relevance to Japan?

Is there any relevance to Japan?

Even if not a problem on the scale of the US other countries have also opioid overdoses as well, so there may be some relevance. But probably is more important that some people will mistakenly think that using more of a drug for treatment is always better and articles like this can help those people understand it is not so simple.

Is there any relevance to Japan?

Good point. No relevance to Japan as there are no opioid overdoses.

Higher-dose naloxone spray for reversing opioid overdoses didn't save more lives, researchers find

Yes, because everyone got a high dose regardless if they used a lower-dose spray

If they want to find out if there's a difference get data on those who got a low dose

Good point. No relevance to Japan as there are no opioid overdoses.

Any reference for this claim? of course it was already explained how there is relevance even if the cases are fewer than in the US.

Yes, because everyone got a high dose regardless if they used a lower-dose spray

If they want to find out if there's a difference get data on those who got a low dose

The data compares the results from patients treated with 4mg and those treated with 8mg, that is what the text you quote describes, the lower dose is enough to save lives and no benefit is there in increasing that.