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New technology can create treatment against drug-resistant bacteria in under a week

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By Kristen Eller

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Interesting; obviously still a long way short of a useable therapy in humans. Much work yet to be done. No doubt the up beat write up is aimed at eliciting funds to continue the research. Certainly worth investigating as if the problems can be overcome it looks to be a useful tool in overcoming a looming crisis in antibiotics. Of course we shouldn’t have a looming crisis but for the massive misuse of antibiotics worldwide in both humans and animals in the past and still continuing today.

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Developing the molecules was never the problem. It is the clinical trials that takes the majority of the money and time, even if you have the molecule ready, it will still take 5-10 years minimum to bring it to use.

No time like the present get started ! The sooner this is perfected the better.

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This is not a breakthrough as they made it seem, many technologies can do that. Developing the molecules was never the problem. It is the clinical trials that takes the majority of the money and time, even if you have the molecule ready, it will still take 5-10 years minimum to bring it to use.

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Good start, but some ways to go before it can be widely used. As it might kill you at the same time as bacteria.

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As our study only tested our new strategy on cell cultures in the lab, we’ll also need to see how it works in living animals to maximize the effectiveness of this kind of treatment.

And this is actually where the difficult part of the work is, so the author seems way too optimistic about the research, synthetic nucleotides like the PNA are expensive to produce, the delivery to the target cells is difficult and they can produce a lot of unexpected side effects, specially at the doses needed to replace the function of antibiotics. Talking about how good they are before even beginning experiments in vivo is not justified.

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