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UK scientists to track mutations in coronavirus to map spread

By Kate Kelland

UK scientists are to track the spread of the new coronavirus and watch for emerging mutations by using gene sequencing to analyze the strains causing thousands of COVID-19 infections across the country, Britain said on Monday.

Researchers will collect data from samples from infected patients in England, Wales, Scotland and Northern Ireland, the government said in a statement.

At least 281 Britons have died from COVID-19, the disease caused by the new coronavirus that has spread around the world in a pandemic.

"This virus is one of the biggest threats our nation has faced in recent times, and crucial to helping us fight it is understanding how it is spreading," said Sharon Peacock, director of Public Health England's (PHE) national infection service.

Working in teams across Britain, scientists will map out and analyze the full genetic codes of the COVID-19 samples.

"Genomic sequencing will help us understand COVID-19 and its spread. It can also help guide treatments in the future and see the impact of interventions," Patrick Vallance, the government's chief scientific adviser, said in the statement.

In epidemics, genome sequencing can help scientists monitor small changes in the virus at a national or international scale to understand how it is spreading and whether different strains are emerging.

"Right now, the important questions we can help answer with sequencing are to help understand the role of international importations into the UK," said Nick Loman, a professor of microbial genomics and bioinformatics at Birmingham University.

The 20 million pound ($23 million) project, called the COVID-19 Genomics UK Consortium, will be co-led by the Wellcome Sanger Institute, which specialises in genetic research, PHE and other public health agencies, as well as the National Health Service and several academic institutions.

"All viruses accumulate mutations over time, some faster than others," said Paul Klenerman, a professor at Oxford University who will be involved in the work. "For Covid-19, this has only just begun - but this emerging variation can be tracked in detail."

© Thomson Reuters 2020.

©2020 GPlusMedia Inc.

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Good. Tracking mutations can help find a vaccine.

0 ( +3 / -3 )

@Ludd: Finding mutations sets back vaccine development.

-2 ( +2 / -4 )

Finding mutations sets back vaccine development.

I don't think finding mutations sets back development. Not knowing about any mutations is surely a bigger setback.

(I'm not an expert.)

2 ( +2 / -0 )

Finding mutations sets back vaccine development

Not necessarily, if you have a protein that is a good target for the antibodies but find a lot of mutations in one part of it, research can focus in the part where the mutations are not happening.

Instead of blindly trying with something that changes all the time the vaccine is produced with the part that does not and it will be more likely to produce useful results.

4 ( +4 / -0 )

Yes, trace the real roots and then U will find the answer.

-4 ( +0 / -4 )

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