Weight loss drug safe, effective for under-12 kids: study

I have a better alternative...feed them healthy food and make them go outside and play!

Excluding those unlucky few who have medical issues affecting their weight... Parent allowing/facilitating their kids to become that fat in the first place need to be prosecuted for abuse

Kids taking drugs to reduce BMI by 5%!

Put money into preventing the problem not curing it!

Exercise and healthy eating. It isn't rocket science!

Cake is an exceeding healthy food in moderation so maybe make the fat kids do exercise then reward them with a French Fancy or Bramley apple pie?

I can understand the pharma industry wanting to get customers conditioned from increasingly early ages, but as stated above, with proper diet and exercise the problem need not exist.

Lead study author Claudia Fox of the University of Minnesota said that kids living with obesity are currently told to just "try harder with diet and exercise".

A major problem is that the dietary advice that is usually given is completely inadequate.

After a little over a year, 46 percent of the children receiving the drug saw their body mass index (BMI) shrink by at least five percent, according to the study.

So 54% of the children receiving daily injections failed to reduce their BMI by 5%!

And considering that the weight loss from this drug is often mostly loss of lean mass. Definitely not worth the risk of severe adverse effects.

So 54% of the children receiving daily injections failed to reduce their BMI by 5%!

I'm guessing someone forgot to account for the fact that kids are also growing at that age...

So 54% of the children receiving daily injections failed to reduce their BMI by 5%!

I'm guessing someone forgot to account for the fact that kids are also growing at that age...

That could be relevant if we're only talking about reducing weight. I would not expect these kids to just grow fatter, without increasing in height, especially with daily injections of this risky drug....

That could be relevant if we're only talking about reducing weight. I would not expect these kids to just grow fatter, without increasing in height, especially with daily injections of this risky drug....

Yes, because bone and muscle density are consistent through childhood, right Mr. Scientist?

 I have a better alternative...feed them healthy food and make them go outside and play!

Parent allowing/facilitating their kids to become that fat in the first place need to be prosecuted for abuse

Exercise and healthy eating. It isn't rocket science!

Healthy food choices, and knowledge thereof, and safe places to play aren't accessible for everybody.

So 54% of the children receiving daily injections failed to reduce their BMI by 5%!

And 91% of children not receiving them.

Definitely not worth the risk of severe adverse effects.

Obesity is riskier.

A major problem is that the dietary advice that is usually given is completely inadequate.

What dietary advice would you give these children?

What dietary advice would you give these children?

This question is great because the answer exposes the problem with their ‘you can’t trust anyone but you must trust me’ stance. But then, I’d they say you can’t trust anyone, then they just expose themselves as nihilists. And then if they say someone else can be trusted they’re hypocritical for saying anyone can be trusted. So they’ll say ‘think for yourself’ forgetting that by definition half of people are below average intelligence.

I wonder how the people who don't trust experts, figured out not to trust the experts. Did an expert in not trusting experts give them their expertise in not trusting experts, meaning they trusted an expert to not trust experts? Or did they spontaneously stop believing experts all on their own, and inadvertently become experts at not trusting experts, spreading their expertise in not trusting experts to people on the internet. The expertise of not trusting expertise.

And am I now the expert on experts on not trusting experts?

Can you trust me?

Data

The average starting BMI of the children in the study was 31, the average age was 10 and the average weight was 70 kg. The drug is not intended to replace but supplement a healthy diet and exercise to bring those massively obese children "off the ledge" before they develop life-threatening health problems.

If they are given food instead of junk and do move their bodies (no particular exercise needed for children), they do not need any "supplement". That is just an excuse for the pharma industry.

A major problem is that the dietary advice that is usually given is completely inadequate

Is your PhD in a the area of diet and nutrition?

You told us you were a credentialed scientist but never told us what your doctorate was in.

It’s just that some regurgitate what they watched on a podcast and then appeal to conspiracy theories if anyone questions their opinion.

Many of them follow a carnivore diet.

That is just an excuse for the pharma industry

Right on cue.

Surely, weight loss drugs prescribed for children should be a last resort?

I have to say I rarely see child obesity in my community, although how that is defined requires knowledge of the subject.

I am reading, adults administer these injections in the stomach, I under the doses can increase if the patient weight loss in deemed insufficient.

餓死鬼

What dietary advice would you give these children?

The simple answer is "eat food" instead of overprocessed junk. I hope you do not not need an explanation.

Many of them follow a carnivore diet.

And many of their podcasts are hosted by useful idiots to kremlin money, now under indictment by the DOJ.

These are kids. They eat what is provided. The advice needs to be given to guardians to give the kids proper food.

Same with advice on other factors

The simple answer is "eat food" instead of overprocessed junk.

That was the advice given to the children who received the placebo and were "encouraged to exercise and eat healthily." 91% of the time, it didn't work.

Simple answers to complex issues are like giving someone a flu shot when their hair is on fire. Not helpful.

Hawk

That was the advice given to the children who received the placebo and were "encouraged to exercise and eat healthily." 91% of the time, it didn't work.

The advice should of course be given to the parents who control what their children eat, and not the children. I thought that is obvious.

The advice should of course be given to the parents who control what their children eat, and not the children. I thought that is obvious.

Yeah, because the parents were in no way involved with these studies performed on their under 12-year-old children. They weren't asked for their informed consent or involved in consultations which were obviously conducted before taking such extreme measures, or privy to the parameters of the study. I mean, do you think people can simply conduct medical research, including invasive procedures, on minors without informing their parents? Really?

Here is something interesting.

Asians from Japan, China and South Korea that immigrate to north America, have low obesity and low cardiovascular problems, by the first generation born in North America they are near equal with the rest of the north American society and develope coronary problems and obesity by the 2nd generation they are at the same levels as the non Asians.

This is due to the fact the immigrant generation continues eating like they did in the country of birth but later generations end up eating the same junk as the non Asian population.

In other words, prepared food, high cholesterol, fat, calories etc...

Japan the average daily calorie intake is 1,900 to 2200 but in North America and Europe it is 3500.

A major problem is that the dietary advice that is usually given is completely inadequate.

What dietary advice would you give these children?

Eat real food and cut the carbs. For obese people, they should ideally cut carbs completely.

Carnivore is good, but keto is fine too.

Their BMI will decrease faster and they'll be healthier than with these risky drugs.

Eat real food and cut the carbs. For obese people, they should ideally cut carbs completely.

Carnivore is good, but keto is fine too.

Their BMI will decrease faster and they'll be healthier than with these risky drugs.

Links to any respected medical organizations that agree the keto diet and or carnivore are safe long term?

I have a funny feeling this testing was done in low socioeconomic areas where parents are also overweight and, let's face it, not the sharpest knives in the drawer. As a result, the kids wouldn't be well supervised regarding the food they ate or exercise they did even if the parents themselves were given good dietary advice, because the parents either lacked understanding of the advice or the willpower to implement it. This risks skewing the outcomes of the control group to make the drug results look better.

Eat real food and cut the carbs. For obese people, they should ideally cut carbs completely.

Carnivore is good, but keto is fine too.

Their BMI will decrease faster and they'll be healthier than with these risky drugs.

Links to any respected medical organizations that agree the keto diet and or carnivore are safe long term?

Naah, the medical organizations you consider "respectable" are heavily funded by big pharma and big food. That's why the problem is just getting worst. The people want to do the right thing and be healthier, but they are always given the wrong advice. I have no respect for those corrupt organizations.

You have a funny feeling but not the inclination to go find the study and figure out if your daydream has any basis in reality?

Maybe I will if I have time. This is a suspicion I have just from reading the press release. I assume you already know all the details, so there's no need for you to consider it further.

Raw BeerToday  04:03 pm JST

A major problem is that the dietary advice that is usually given is completely inadequate.

What dietary advice would you give these children?

Eat real food and cut the carbs. For obese people, they should ideally cut carbs completely.

Carnivore is good, but keto is fine too.

Their BMI will decrease faster and they'll be healthier than with these risky drugs.

Mate, I think you triggered the Dunning-Krueger Gang, a band of hapless outlaws terrorising JT with flaccid insults fired from their popguns.

Eat real food and cut the carbs. For obese people, they should ideally cut carbs completely.

Carnivore is good, but keto is fine too.

Their BMI will decrease faster and they'll be healthier than with these risky drugs.

As always, first consult with a health professional.

As a parent you are responsible for their welfare. If you are overstuffing them to the extent that their health is in danger this should be classified as neglect and the parents should be charged a special tax to pay for the future health problems their exceedingly chubby kids will have. Other tax payers should not be burdened by those who choose to be obese.

Eat real food and cut the carbs. For obese people, they should ideally cut carbs completely.

Carnivore is good, but keto is fine too.

Their BMI will decrease faster and they'll be healthier than with these risky drugs.

As always, first consult with a health professional.

Unfortunately, for too many people, consulting with a health professional has not been very helpful.

BTW, what is more profitable to a doctor, prescribing and providing daily injections of a this new expensive risky drug, or telling their patient to cut carbs?

Unfortunately, for too many people, consulting with a health professional has not been very helpful.

Right. And posters on news sites who have the same answer for every problem - and only the most unscientific "study" ever conducted to back them up - are the key.

Good work this, get em while they’re young and make dough. Only 9% get bad side effects, don’t worry about that, there will be another pill or jab along soon to suit you.

BTW, what is more profitable to a doctor, prescribing and providing daily injections of a this new expensive risky drug, or telling their patient to cut carbs?

They profit either way, because they make you pay for a visit. That's why one should never ever visit a doctor and exclusively listen to medical advice from anonymous accounts on the internet. That'll show 'em.

Daily or weekly injections for life is more profitable than one consultation fee.

Whenever there is a diet article the same so-called experts flock like birds repeating the advice they have posted in every previous type of article.

Whenever there is a diet article the same so-called experts flock like birds repeating the advice they have posted in every previous type of article.

Yeah and the same flock of posters telling us that pharma products are great and that we should listen to the doctors, which have so far been completely useless.

Is it just me, but some governments,companies, seem to make a ton of money off people who get fat, overweight and sick.

They get the sales tax everytime they buy something unhealthy.( the fat unhealthy time won't kick in for about 30,40 or 50+ odd years due to the creaping lag of time that passes). Then when they do get sick, we ask them to change, so they pay even more money to go to the gym, pay someone to teach them to diet,pay to see a psychiatrist, then expect the health service to clean up the mess. (for free at the point of delivery) or they have to pay for it at the hospital or via taxation. But the one person who loses is the rather fluffy person.( can we say fat?) , and the one who makes money is either the drug company, the diet companies, the gyms, and someone is creaming in the money. Japans school system has got it right. They grow up learning about food, and health not growing up about what food makes me feel happy for 5 minutes. There won't be much use for that drug on Japan.Except in rare cases. Boom town in the UK and the USA. Fatty heaven over there.

The simple answer is "eat food" instead of overprocessed junk. I hope you do not not need an explanation.

That is a simple answer. I personally don't think I would be able to give credible dietary advice since I'm not a dietician, the person's doctor with access to their medical records (allergies, health conditions etc.), a scientist researching the effectiveness of different diets or related drugs, or someone who has read half the journals on the topic. I suppose with my level of expertise, I would probably also say something like "eat food" and "do exercise".

Eat real food and cut the carbs. For obese people, they should ideally cut carbs completely.

Carnivore is good, but keto is fine too.

Their BMI will decrease faster and they'll be healthier than with these risky drugs.

I too prefer to avoid taking drugs whenever possible. However, people may not always have a better option. Also, I'm not sure about recommending restrictive diets that I have yet to find any conclusive research on their long-term effects (I did have a listen to Dr. Baker responding to some criticism on his promotion of the carnivore diet and it didn't seem he had anything conclusive either).

Put money into preventing the problem not curing it!

Or as currently done, put money on both, the prevention part is not working thanks to many different factors, so preventing and curing it seems a much better alternative

A major problem is that the dietary advice that is usually given is completely inadequate.

Unfortunately a lot of people feel they have a better understanding of human nutrition than the whole of the scientific and medical community of the world, thus giving dietary advice that is terribly bad.

So 54% of the children receiving daily injections failed to reduce their BMI by 5%!

Since the injections only make the lifechanges easier that is still huge, it is not like the drug automatically make the children or their families change their diet and excercise by magic.

If they are given food instead of junk and do move their bodies (no particular exercise needed for children), they do not need any "supplement". That is just an excuse for the pharma industry.

This overly reductionist approach is what has caused the obesity epidemic in places like the US, the experts are long above this completely inadequate approach. Not to mention that the children do eat and excercise better in order to lose weight.

The advice needs to be given to guardians to give the kids proper food.

And it is, which makes little difference since the problem is much more complicated than people not knowing what is better to do, if it was that easy both groups on this study would have the same reduction.

Eat real food and cut the carbs. For obese people, they should ideally cut carbs completely.

Terrible dietary advice, the actual experts do not say cutting 100% or carbohydrates is desirable nor healthy.

Carnivore is good, but keto is fine too.

According to the evidence, carnivore is risky and unhealthy, and keto is bad as well.

I have a funny feeling this testing was done in low socioeconomic areas where parents are also overweight and, let's face it, not the sharpest knives in the drawer

Yet the children of families where the intervention was the same except for placebo did not lose weight, which makes the argument obviously false.

Naah, the medical organizations you consider "respectable" are heavily funded by big pharma and big food. 

This is still the same excuse every antiscientific group tries to use when confronted with absolute lack of evidence and scientific support "The Earth is flat but all the scientific institutions are on the pocket of big space, and are in a conspiracy to hide it" "The planet is only 6000 years old but..."

Unfortunately, for too many people, consulting with a health professional has not been very helpful.

In general, health professionals are the ones more likely to be helpful by much, specially when compared with people that willingly gives bad advice contradicting the available evidence.

Daily or weekly injections for life is more profitable than one consultation fee.

So are useless books, supplements, personal coachings, etc. The difference is that the drugs do work and reduce the risk for the patients.

Is it just me, but some governments,companies, seem to make a ton of money off people who get fat, overweight and sick.

Governments? none, the public money spent greatly surpasses what is made by the government with the treatment, and this is why they also have a responsibility to put order into the insurance/health system. This of course happens in most countries, with the obvious exception of the US, that has the most expensive system while being also one of the least effective between developed countries.

If you have any health issue consult a health professional.

Of course you can also research on your own and try to cure yourself.

Who knows after decades of trial and error you might stumble onto something that works for you.

That seems to be the case for some here good that something finally seems to work hopefully it can be sustained

I just want to say that no you don't know what advice the health professional will give you.

It will depend on many factors and varies between individuals.

And usually they give options among which you can choose what you think is best suited for you

Also, I'm not sure about recommending restrictive diets that I have yet to find any conclusive research on their long-term effects

Cutting out dietary carb is not any more restrictive than cutting out alcohol. There is no need for it.

Cutting out dietary carb is not any more restrictive than cutting out alcohol.

Any links to respected medical organizations that agree? Or which "experts" are you getting your information from? Or is it just "feeling"?

Raw Beer

Today 09:23 am JST

Also, I'm not sure about recommending restrictive diets that I have yet to find any conclusive research on their long-term effects

> Cutting out dietary carb is not any more restrictive than cutting out alcohol. There is no need for it.

It is needed for healthy living.

The body manufacturing glucose because of absence of dietary carbs is inefficient and unhealthy.

And by going on unbalanced diet long term you will not get enough of essential nutrients and too much of others.

Cutting out dietary carb is not any more restrictive than cutting out alcohol. There is no need for it.

That is not what the medical consensus says about a healthy diet.

Once again, pretending every single institution of the world contradicts you because of a supposedly global conspiracy is not an argument against this fact, it is just an excuse people without any evidence or valid arguments use. It is not rational or even believable. Zero carbohydrate diets are considered unhealthy and risky, even if you want to believe differently.

Once again, pretending every single institution of the world contradicts you because of a supposedly global conspiracy is not an argument against this fact

To be fair, it takes a certain amount of intelligence to realize that when all scientists are saying the same thing, it's not a global conspiracy theory.

I mean, it doesn't take that much intelligence, but it takes a certain amount no doubt.

Strangerland

To be fair, it takes a certain amount of intelligence to realize that when all scientists are saying the same thing, it's not a global conspiracy theory.

Wrong on both counts. Firstly, there is never a time when "all scientists are saying the same thing"; rather there are times when the media and institutions suppress opinions from dissenting scientists. And secondly, even IF they were all to agree, that still has no bearing on the truth of the statement. American scientists for a long time agreed that frontal lobotomy cured all sorts of problems, that circumcision is healthy, etc etc. And not even get started on nutrition advice...

Virusrex

Once again, pretending every single institution of the world contradicts you

I wish I had 100 yen for each time you bring up "every single institution of the world".

Talk about the old rethorical fallacy of "appeal to authority"...

Wrong on both counts. Firstly, there is never a time when "all scientists are saying the same thing";

Of course there is, the Earth is not flat, infections are produce by microbes, the brain function is not to cool blood, this is extremely common, just because you ignore something that does not make it false, it just make it much easier for you to be mistaken.

rather there are times when the media and institutions suppress opinions from dissenting scientists.

Unless you can prove actual evidence exists that contradicts the consensus this is just the same old excuse the antiscientific propaganda groups use every time they are confronted with the consensus "The moon is an hologram, it is just that the brave scientists that have prove it is not real are being suppressed". It is just not even remotely believable,

And secondly, even IF they were all to agree, that still has no bearing on the truth of the statement.

Of course it does, the consensus gives weight to the claim since everybody that knows a lot in the field shares the same conclusions. There is such a thing as a valid appeal to authority, it is a perfectly correct argument.

I wish I had 100 yen for each time you bring up "every single institution of the world".

But instead you have 100 yen for free every time you have been able to refute this claim presenting respected institutions of the world that contradict the consensus.

That would still amount to zero to this day.