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© 2021 AFPPfizer CEO: Vaccine third dose 'likely' needed within 12 months
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© 2021 AFP
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CoffeeDeluxe
Pfizer CEO: Vaccine third dose 'likely' needed within 12 months
Maybe Moderna or Sputnik is the way to go, then.
iraira
Unfortunately, resistance to coronaviruses often fades over time. Booster shots will keep certain immunogloblin levels high and should offer smore sustained resistance. As exposure to other coronaviruses seems to impart some cross-resistance to other coronaviruses, research is also being conducted on other (much less lethal) coronaviruses in hopes that they can immunize against COVID-19 using more benign coronaviruses.
bokuda
at this pace I we won't live long enough to need a 3rd vaccine.
Concerned Citizen
Another booster shot needed? I thought the vaccine 'works'?
This might be part of Big Pharma's great business model for long term profits with no risk.
Never let a good crisis go to waste. (Covid)
Create a solution vaccine that 'works' but doesn't always work or work very well, so you need perpetual booster shots.
Heavily fund politicians on both sides of the political aisle and pressure them to pass laws to make vaccines mandatory and to also free you from liability for the deaths and injury resulting from your product.Amazing!
virusrex
Overly pessimistic declaration not really based in evidence, maybe it is just something convenient (for him) so he can believe this possibility much more easily. If immunity waned enough to allow reinfections it would have been visible already in clusters of cases between people that were infected a year ago. Before this is seen there is no real need to think this "necessary extra booster" is the only possibility.
This is the problem, for COVID cellular immunity has already been proved to be very important, maybe much more than antibodies, but it is much more complicated and expensive to examine, so everybody is just doing the least effort approach and keep looking only to the antibodies and try to conclude things from it.
For some pathogens (like Cytomegalovirus) it is very complicated to develop vaccines because of this, in animal experiments a vaccine protects 100% of the animals against a dose of virus that would have killed them, but antibodies are never detected. The vaccine candidate apparently works but its just too complicated to test it on humans.
didou
A few words.
He starts to prepare and accomodate the world, before saying a yearly vaccine might be necessary.
jinjapan
Seems similar to the influenza vaccine which lasts about 6 months. Many people get those shots every year. Have to get used to the new world I guess.
venze
So Pfizer, the big pharma, says a 3rd dose may be necessary in 12 months time. Why not just announce that there will be a 4th dose in another 12 months later, and so on..
Utterly unbelievable and unacceptable..
virusrex
Sorry if reality don't adjust to the terrible things you want to believe.
No evidence until now that any extra dose is necessary, after a year of infections. This should be something good and motive for celebration, what kind of people would wish for the opposite only so they can feel their irrational beliefs on imaginary conspiracies vindicated?
CoffeeDeluxe
No Thanks ..99.7 % survival rate....I'll take my chances
nandakandamanda
Luxury!
That people can worry about the remote possibility of a third shot, when most of us have had no shots at all... nowt, nil, nada.
Eppee
I remember having multiple shots when I got vaccinated against the hepatitis B.
Or the booster shots every couple of years you get as a kid. Even as an adult aren't we supposed to get boosters every 10 years or so on our current vaccines ?
Ricky Sanchez
The more shots the company says you "need", the more money they can make. Imagine that!
n1k1
Doesn't really makes much difference for Japan does it ? Japan can't do the the first , a third shot ?! LOL
For most Japanese that is really far in the future , like 2045 and flying cars, space tourism and everything ...
moonwatcher
Rolf, many peeps here would seem to rather go back to the dark ages and take the chances of staying alive at fifty percent to any type of infection. Ya they would rather listen to Gym Jordan instead of Fauci. As if new diseases were never going to plague mankind. Consider yourself fortunate for whats being provided you ungrateful worms.
Blacklabel
whats the point of vaccination.... if in a room of vaccinated people, in a place where you have to be vaccinated to enter....you still have to social distance and wear one or double masks?
https://en.wikipedia.org/wiki/Cabinet_of_Joe_Biden#/media/File:Cabinet_of_President_Joe_Biden_in_2021.jpg
Hito Bito
People are shrugging this off, blithely comparing repeated COVID injections to flu shots. By doing this, you miss most of the Big Picture.
Most people aren't forced to get flu shots. But there are real world penalties for not getting this (soon to be annual) COVID injection. Will you be able to board a plane, enter a hospital or retirement home, or visit another country, from here on out, without "consenting" to a "voluntary" annual jab, along with paying for the privilege of having your DNA collected before and after your trip, in the form of mandatory PCR tests? Do you have to carry around "passports" with you at all times to prove to all and sundry that you've received a flu shot, as is now being "strongly" recommended in the US and throughout Europe? No, no you do not.
Also, unlike common flu shots, most of these COVID vaccines actually introduce RNA-altering instructions into your body to actually change the way your body function, in a fundamental way. It's quite revolutionary, since it's being introduced now a a global scale, yet with not 10% of the previous clinical trial and test times required by former vaccine technology. Problems with blood clot issues, for example, only appeared not in the trial stage, but while vaccines were being introduced into the general population at large, which only further confirms the "rush-job" now underway.
To conclude, saying this COVID vaccine is "just like the flu shot" is about as wrong as claiming that COVID is "just the flu". It's not, in so many fundamental ways.
Sven Asai
Now we come the truth some nearer. Yearly updates needed, long COVID symptoms, new variants escaping the immune response... it all leads to what I would at least call a severely diminished average life expectancy. Think for yourself, you get quickly into the higher age groups with the much higher risks and you also don’t know if you really don’t develop those blood clots during the next ten or twenty years’ vaccinations. No, that’s not the way out of the pandemic and I told you so. We have to extinguish them with a long strict lockdown once and for all. Cannot you see it yourself? And if not, why?
sf2k
This is likely due to observational studies that showed people who recovered from COVID-19 had their antibodies diminish over time, so the body memory cells weren't remembering the infection. They'll assess it at the time and if the antibodies are gone then we're essentially waiting for a better vaccine. Think of the Pfizer/Moderna as staging intermediary steps
virusrex
If by big picture you mean the content of your comment that is good, because you make many serious mistakes.
Everybody is being subjected to social distancing measures, if the vaccines can replace some (something not yet proven, but quite strongly hinted by the data) then it is a normal consequence that people would prefer a safe and effective immunization instead of a continuation of their current situation. You don't? then you can continue as now.
The vaccines do NOT contain "RNA altering instructions" that is a fundamental mistake, RNA are the instructions, protein produced and the RNA is destroyed in the course of hours, without anything left in the body but the protein produced. The viral infection on the other side, that is a much more complicated and toxic process, with the RNA actually being replicated trillions of times over the course of infection and actually producing proteins that modify how your cells work so your immunity is altered and the virus can survive.-There is no real possibility yet of needing yearly doses, even if the Pfizer CEO says it, because there is no data to indicate it. There is only one serotype of SARS-CoV-2 in all the time since it jumped to humans, that means it is entirely possible the protective immunity can last more than a decade (as in the first SARS) or even for life. Also, it is not like the Pfizer vaccine is the only one available, or that other maybe much better are not being developed and tested right now.
-There are much more simpler ways to collect DNA from you, specially because the PCR kits are based in the collection of RNA, not DNA. In order to get meaningful results the DNA from the sample is actually considered a contaminant and destroyed during the process.
Ah_so
Depending on your age group. Much higher in later years. And keeping the prevalence of the disease down reduces the chance of mutations that could increase its mortality rate.
And what's the survival rate of the vaccine?
Blacklabel
not trying to give you a hard time.
Thats scary. this would mean that the virus will be with us forever as long as even one person has it? Which would always be the case if the vaccine cant KILL the virus.
So we can never do anything, will always be wearing double masks and will be doing our best until our deaths...from something else? scary again.
theResident
@SvenAsai: And what happens to the workers of Japan under your strict lockdown? Nobody here, unlike elsewhere in the world is being compensated for staying at home - that is unlikely to change. So, your wish is for financial suicide for most citizens here?
virusrex
Not really, that is not a realistic possibility, once we can reduce the risk from COVID to the same levels of what we already deal with (Influenza and other respiratory viruses for example) then there would not be a point in doing something special for COVID. If enough people are immune to the disease this point can be reached relatively soon. Even if it becomes endemic only few people would get sick from it, vulnerable population would be protected and we would have all the time in the world to find better treatments or vaccines.
Raw Beer
Those who recovered from the previous SARSCoV 17 years ago are still immune.
Seth M
How about 365 times a year?
Or may be they can make a drug that you take one tablet every day to achieve the immunity
theResident
@Raw Beer: A Doctor now, are you? You have proof that having had COVID 19 - a person will remain immune.
bob
Imagine the hubris of an anonymous internet poster telling us HE knows more about the Pfizer vaccine than the CEO of....Pfizer.
Also interesting that this admission was more than 2 weeks old before being reported by the MSM.
Everyone paying attention? Good. Now lets see what happens when they admit its a vaccination needed every 6 months.
"Got your passport in order, sir?"
"Ah, sorry. It says here you haven't been vaccinated since last month. We can't let you on the plane"
iraira
Different virus. Different characteristics.
Huang et al "A systematic review of antibody mediated immunity to coronaviruses: kinetics, correlates of protection, and association with severity" in the journal Nature Communications, shows that immunity to many coronaviruses is often transient.
lostrune2
Nobody knows yet exactly how long the Covid-19 immunity lasts. So far, studies have shown at least 6 months
The Pfizer CEO is just exploring a possibility - especially the more variants there become
Here's the reason: the more differences between the new variants and the original virus, the less effective the original vaccines. If the new variants look like a whole new virus, then of course your immunity would be less likely to recognize it. So that's where booster shots (that factor in the new variants) come in
That's why don't keep spreading the virus - the more the virus spreads, the more it replicates, the more mutations that could produce more variants
And the vaccines have a 99.99% survival rate, so take your chances with that too
(Plus you may be helping spread the virus - since you won't know when exactly you got infected and thus may be infecting others in the meantime you're asymptomatic. Spreading the virus = more variants)
It's the 2nd jab where ya may see a more pronounced immune reaction - but that's a good sign because that means your body remembers the previous intruder and knows to mount an immediate response the 2nd time around
Wolfpack
If you don’t have pharma stock this might be your last chance to get in before it really hits the roof.
virusrex
Better yet, imagine that this is what the scientific consensus is, not what any single person do. But people unable to understand science think everything is a personal declaration because that is how they do things, basing their comments solely in their own opinion instead of the presence or absence of evidence.
"Admitting" only works if this is proved first by evidence, without any scientific basis it is just "said". Can you provide this evidence or we are just supposed to believe you?
Because it depends on broadly neutralizing immunity thanks to their mild course, and "transient" still means over the course of several years, comparison with the highly pathogenic coronavirus infections is obviously much more likely to be closer to COVID, and this is already been discovered to be cellular immunity based and long lasting. As you said, different viruses different characteristics, the more distance you take from this virus the more differences you will find in their characteristics.
Desert Tortoise
Have you ever heard of the "Yellow Card", i.e. the International Card of Vaccination and Prophylaxis (ICVP)? Vaccination requirements have been a feature of foreign travel almost since the first vaccinations were developed. Such requirements are currently in effect for Yellow Fever, Polio, Meningococcal meningitis and until 1981 for Smallpox. The requirements usually only affected travel to and from nations where these diseases were prevalent but nonetheless they exist to this day. No Yellow Card? No entry, no exceptions.
bob
Don't look now, Rex. The "scientific consensus" just banned AZ and JnJ in many countries.
Wow! We'd better alert all those travelers going from New York to LA with that stopover in the Congo.
virusrex
Look at the meaning of the word "ban" it does not mean what you think it means.
bob
ah terribly sorry. Its been "paused" if that makes you feel better. You say toMAto.....
But a very interesting development for someone, Rex, that assured everyone about 10 days ago that all the vaccines were perfectly safe.
And now even cheerleaders from the Atlantic are sounding the warning bells about Pfizer....
When was the last time you were right about anything?
I know it hasn't been in the last calendar year....
virusrex
Yes, surprising but completely different words have completely different meaning, who would have known!
Now, where exactly did I supposedly sayt that all the vaccines were perfectly safe? Its not like you pulled that out of thin air, right? Of course you would not let me prove you wrong on this.
The reality, and what is still true right now is that all vaccines are much safer than COVID, which is the purpose of a vaccine. That is still the consensus of science and why the vaccines are not "banned". Vaccinating still means the people immunized have a lower risk of health problems or death, even from clots.
virusrex
Please do, I mean you have still not found where I said that vaccines were perfectly safe, Or you can also accept this was not true and you were wrong.
Saying that vaccines have evidence of safety and efficacy, or that have a degree of safety enough to be used in adults is still the same, they are much safer than COVID and people are safer from clots being vaccinated than if not, that still is not saying that vaccines are "perfectly safe" as you wanted to misrepresent.
Txrogers
Of course Pfizer's CEO would suggest such a requirement. And his miracle jab is the cure for it all.
“Show me the incentive and I’ll show you the outcome”. Charlie Munger’s quip is typically insightful and relevant to many of the ructions currently facing the economy and a number of the key sectors within it.
And we understand Pfizer's CEO incentive to a tee. As for the endless and repetive diatribes by Viralex types becomes, the less credible the message. Big Pharma seems unable to grasp the concept of diminishing returns I suppose.
I would give this a listen: Covid 19 and Lockdowns: The Ugly Truth | Nick Hudson | Co Founder of PANDA. Youtube keeps deleting it, and it keeps getting uploaded.
https://www.youtube.com/watch?v=8hPM8kCiD-c&t=427s&ab_channel=KenyaDigitalArchives
Obviously not so blind this whole debacle.
Raw Beer
@bob
Amazing isn't it? Pushing these vaccines on kids is sickening, but I'm not surprised.
I believe the "at least 6 months" refers to the actual antibodies. However memory lymphocytes will likely be long lived.
Not so different, serum from the 2003 SARS patients cross reacts with SARSCoV2.
virusrex
The evidence is still clear and the science solid, vaccines are safer than COVID, there is no evidence that indicates that yearly vaccines are going to be necessary, Who says it has no importance, the original data is the one with weight, even if it demonstrates something that you don't like.
Nick Hundson keeps being deleted not for saying controversial things but because he keeps defending things that can easily be proven false or deeply misleading, there is no point in listening to anyone that willingly chooses to misrepresent things to give a false impression. The same as people that criticize others for saying that vaccines are "perfectly" safe when that is simply false.
https://factcheck.afp.com/anti-lockdown-group-promotes-misleading-claims-about-face-masks-fact-check
bob
Not surprising in the least. The vaccine has become holy water for so many who shun religion.
case in point..
A journalist proclaimed she would "love to die" from the AstraZeneca vaccine if it would 'help others'
If she's under 40, she's got a greater chance of her wish coming true than from dying from Covid.
bob
You can also be sure the ghouls who want this for children don't have children.
Raw Beer
@bob
I agree.
@Txrogers
Excellent! Good summary of much of the propaganda we've been bombarded with for a year.
virusrex
There is nothing goulish about people wanting to lower the low but very real risk children have of serious complications from COVID specially because long term problems are still a very likely complication that will become clear only in the future,
This wrong idea comes from having the preconceived idea that vaccines are impossible to be safer than the infection they prevent. This is completely illogical, specially because the vaccines have note even been tried in the kids.
What would you think if she said that to prove the vaccines are unsafe?
virusrex
Unfortunately is based on misleading and false information. It gives the impression that if he limited himself to say things proven and clear he could not make the points he wanted to make.
Raw Beer
What specifically is misleading and false? Did you at least watch the video? He provides many statements directly from the CDC, journals,...
It's like he is just spouting out random words together with "scientific consensus, science, rational, professional association ...."
Raw Beer
It's not like he is just spouting out random words together with "scientific consensus, science, rational, professional association ...."
Sven Asai
Almost, @virusrex....Although this is true for the big majority, there are seldom constellations when it might happen that the vaccinated mRNA alters the DNA in human cells’ nuclei. Most exposed , as I’ve read, are HIV patients with severe symptoms and a certain strong medication, but maybe you know that already and even more in detail.
virusrex
I already provided a link like several there are where collected many of the lies and inconsistencies of his arguments. Most of what he uses in the video is either deeply misleading or plainly false. From the naming of the virus (which is not problematic at all, it follows all the Taxonomy of Viruses guidelines and rules), jumping to false conclusions (people are wrong by saying that most of the population is susceptible to infection because not all die from it?) he keeps taking the number of infections and deaths out of the context of the measures being done in most countries, as if they had no impact and the deaths would be the same without them, he also keeps repeating one single example as if the scientific consensus was all based on empiric evidence, etc. etc. In general that is not something a person interested in being truthful would do.
I mean, the evidence of the effects of lockdowns have absolutely nothing to do with China, but for some reason he skips it all and makes it sound as if the world was following their example blindly. That would be enough to know why he keeps being deleted for misleading and false information.
Those random words you make no effort to understand is precisely why he cannot be taken seriously. He is contradicting the scientific and medical community with deeply insufficient arguments and almost no data to support his conclusions.
virusrex
Sorry but that is false information. Or maybe you are confused about what you saw. I can help you with that if you put the reference.
Reverse transciption and genomic integration is a very specialized mechanism that requires a specific combination of RNA sequences and (most importantly) a protein that can produce this result, the reverse transcriptase. There is no medication in humans that does that, and HIV patients under active infection do have their genomes altered, but by the HIV and not by other mRNA, if that were the case they would be chocked full of extra genes because the cells contains cuadrillions more mRNA from the normal functioning of the cell than what is provided in the vaccine. This obviously is not happening.