151E comments

Posted in: Kill Japan's elderly? Cannes film probes chilling idea See in context

Sadly, it seems most people are unaware that humanity is on the cusp of a radical revolution in which much of the fragility and weakening the body we associate with aging can be largely mitigated, and in some cases even reversed, such that many people could realistically expect to remain physically active and productive for 120 years plus. I'd encourage everyone to google Dr. David Sinclair and the information theory of aging, perhaps read his book Lifespan or listen to his podcast of the same name.

-1 ( +2 / -3 )

Posted in: 'I’ll kill you!' says Japanese schoolgirl when convenience store won’t let her use toilet See in context

arrested for attempted forced coercion

Oddly redundant. An overly literal translation perhaps?

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Posted in: What Elon Musk's dance with Twitter really means See in context

@Boris Yarovoy

What are you talking about Musk having no long-term goal? He has stated many times that his primary motivation is to make humans an interplanetary species to help ensure civilizations' long-term survival (on the order of millions of years). You badly misread the man.

0 ( +0 / -0 )

Posted in: Zelenskyy accuses West of cowardice in helping Ukraine fight See in context

Makes you think that Ukraine should have kept their nukes instead of joining the NPT

This is exactly why North Korea will never give up their nukes. Most Libyans probably wish they had kept their nuclear program too.

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Posted in: GoFundMe ends fundraiser for Canada convoy protesters See in context

Interesting that GoFundMe supported CHAZ/CHOP despite unlawful activity.

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Posted in: Rogan responds to Spotify protest, COVID advisories See in context

It’s clear many don’t know Jack ‘bout Joe. His show — far from being a fount of misinformation, misogyny, and racism as claimed by the msm — features an eclectic mix of extended unhurried chats with interesting people from all walks of life, including: 

David Sinclair, Andrew Huberman, Rhonda Patrick

Steven Pinker, Richard Dawkins, Lex Fridman

Michael Pollan, James Nestor, Sebastian Junger

Daryl Davis, Josh Dubin, Amanda Knox

John Abramson, Edward Snowden, Bernie Sanders

Alex Honnold, Cameron Hanes, Laird Hamilton

Bill Burr, Russel Peters, Dave Chappelle

Reggie Watts, Penn Jillette, Oliver Stone

Rob Kearny, Ben Patrick, Pavel Tsatsouline

Rickson Gracie, George St-Pierre, John Danaher

His show was one of the first to offer such long form conversation where listeners can hear guest discuss ideas in great detail and length. Calls for censoring Joe because of the views expressed by a small handful of guests flies in the face of liberal claims of tolerance and the once traditional liberal value of free speech.

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Posted in: Neil Young-Spotify row underscores podcast disinformation issues See in context

Strange that Mr. Young thinks mere talk on Joe Rogan's rather eclectic podcast is more harmful than the activities of his Blackstone business partners.

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Posted in: How vaccine misinformation left children vulnerable to Omicron See in context

It's a gamble either way. But taking a wait and see approach with regards to these new vaccines, especially with infants and children, is not irrational given (1) the low incidence of severe disease in children infected with COVID-19 and (2) a 2017 study (Postmarket Safety Events Among Novel Therapeutics Approved by the US Food and Drug Administration Between 2001 and 20100) found that:

*"Among 222 novel therapeutics approved by the FDA from 2001 through 2010, 71 (32.0%) were affected by a postmarket safety event. Postmarket safety events were more frequent among biologics, therapeutics indicated for the treatment of psychiatric disease, those receiving accelerated approval, and those with near–regulatory deadline approval."*

source: jamanetwork.com/journals/jama/fullarticle/2625319

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Posted in: Booster shots needed against Omicron, CDC studies show See in context

Some interesting data from the UK on deaths from COVID-19 in people with no pre-existing conditions shows that, for England and Wales in 2020 (so before vaccines were available), there were:

9,432 total deaths

7,875 aged ≥65

1,557 aged ≤64

with the average age being 81

source: www.ons.gov.uk/aboutus/transparencyandgovernance/freedomofinformationfoi/deathsfromcovid19withnootherunderlyingcauses

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Posted in: Expect more worrisome variants after Omicron, scientists say See in context

According to many of those quoted in the article, we remain ever at risk of more virulent variants as long as large swathes of the globe remain unvaccinated. Given the fact potential animal reservoirs have been identified, how long before we're being urged to vaccinate family pets, livestock, even wild deer too?

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Posted in: Who's next? Hong Kong media fearful after arrests, shutdowns See in context

It's nice to see everyone so worried about freedom of the press in China. I only wish there was equal concern for press freedom in the West and the jailing of Julian Assange in Belmarsh.

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Posted in: Kids' low COVID-19 vaccination rates called a 'gut punch' See in context

If there is scientific data that shows lower risks for children when vaccinated that is reason enough to promote vaccination for them, this is exactly what happens with other infectious diseases.

Not necessarily, especially if the baseline risk is low and the treatment is new with no long term studies. RRR (heavily emphasized by pharma sales reps) needs to be interpreted in light of ARR. Would you vaccinate children in Japan against dengue or rabies (both with much higher CFRs than COVID-19)?

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Posted in: Japan to administer COVID vaccine soon to children aged under 12 See in context

Yes, let's vaccinate the cohort at least risk from COVID-19, the cohort at greatest risk with regard to possible long term side effects of the vaccine, and let's vaccinate them with a vaccine based on a variant no longer widely in circulation. Sounds like a great plan.

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Posted in: Japan chooses to go to the moon See in context

To all the naysayers above - if you're interested in 'saving the Earth', then you ought to be interested in commercial fusion reactors; and if you're interested in fusion, you'll be interested in sourcing helium-3; and if you're interested in helium-3, you'll be interested in mining lunar regolith. So there are good reasons for this renewed space race, especially if you think we should be focused on decarbonizing the economy.

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Posted in: Japan considers bringing forward COVID booster shots for all: Kishida See in context


Thank you for your kind words. I wish you (and everyone else in the comment section) the best of health in the new year.

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Posted in: Japan considers bringing forward COVID booster shots for all: Kishida See in context

Until boosters are available, consider supplementing with vitamin D as recommended in this open letter you can read at vitamindforall.org co-signed by over 220 medical doctors and researchers including:

Dr. Ashely Grossman (University of Oxford)

Dr. Giovanna Muscogiuri (University of Naples Federico II)

Dr. Mirchael F. Holick (Boston University Medical Center)

Dr. David Sinclair (Harvard Medical School)

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Posted in: Top five Japanese prefectures for childhood education expenditure would make any wallet shudder See in context

Many of these prefectures are out in the country where... there may be less of a push to spend on private schools and the like.

One important difference is that private high schools out here in the inaka are generally for those non-academically inclined kids who can't pass the more rigorous public high school entrance tests.

0 ( +0 / -0 )

Posted in: Community transmission of Omicron spreads in western Japan See in context

Most of the Omicron cases discovered in hospital in South Africa were incidental findings, meaning that the patient was visiting the hospital for non-COVID related reasons but were still tested as per hospital policy. So it's likely there are many asymptomatic or only mildly symptomatic people walking around with Omicron infections who would never even think to avail themselves of the free testing services mentioned in the article. Who wants to go out and queue up for testing every time one has the sniffles? A better plan would be to distribute rapid antigen detection tests that can be conveniently used at home, and only then, if the test is positive, go to hospital for confirmation with a PCR test.

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Posted in: Panel recommends no change to male-only emperor system See in context

If they are truly so concerned with ensuring male heirs, they could just quietly employ IVF with PGS, and the public would be none the wiser.

-3 ( +3 / -6 )

Posted in: 19-year-old suspect in murder of sex worker at hotel to be sent to family court See in context

You can enlist in the JSDF at 18, but this POS at 19 is considered a minor and therefore somehow less culpable for pre-meditated murder?!? Would this have been sent to family court if the victim had not been a sex worker?

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Posted in: Kishida says only LDP capable of protecting Japan from security threats See in context

There is some truth in what Kishida says in that the unelected bureaucrats tasked with turning policy into action largely self-identify with the LDP and will work to stymie any policy with which they are not in full agreement.

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Posted in: 5 trails in Japan I can’t wait to hike again when it’s safe to travel See in context

Bit of a pet peeve of mine but the Susoaidaira Valley photo isn't level. Nice shot, but watch those horizons.

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Posted in: COVID-19 deaths of people aged under 60 soar in Japan due to Delta variant See in context

And how many of those had some comorbidity like the teenager in Osaka?

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Posted in: Japan eyes tougher jail sentence for insults to tackle cyberbullying See in context

Well, guess all the those using the hashtag「河野さんにブロックされています」better start watching their online Ps and Qs.

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Posted in: Japanese university developing coronavirus vaccine in form of a nasal spray See in context

Sounds similar to the Rapid Deployment Vaccine Collaborative project. They published a white paper on a DIY peptide based nasal spray vaccine back in July 2020.

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Posted in: Vay unveils ‘teledriving’ as a new path to autonomous future See in context

Hmmm... interesting. I'd still be concerned about the lag time, and about teledrivers watching porn instead of concentrating on the road. At least with a human in the driver's seat they've got real skin in the game.

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Posted in: Medicine is an imperfect science – but you can still trust its process See in context

From the FDA

The FDA budget for FY 2019 is $5.9 billion.

About 55 percent, or $3.2 billion, of FDA’s budget is provided by federal budget authorization. The remaining 45 percent, or $2.7 billion, is paid for by industry user fees.


From NPR, One-Third Of New Drugs Had Safety Problems After FDA Approval (2017)

The Food and Drug Administration is under pressure from the Trump administration to approve drugs faster, but researchers at the Yale School of Medicine found that nearly a third of those approved from 2001 through 2010 had major safety issues years after the medications were made widely available to patients.


It is not irrational to have some skepticism towards new treatments, particularly ones that have had an accelerated development and approval, and ones for which no long term safety data is available.

Yes the current vaccines are an impressive technical development and induce a strong antibody response, but they are also leaky, short lived, and minimally effective against the now most common variants. Furthermore, presenting the immune system with only a single antigen target, is a mistake. It creates strong evolutionary selective pressure in favour of new variants. If the vaccines presented at least three targets, it would make it more difficult for the virus to evade the vaccine trained immune response. This is one reason I'd prefer to wait for a more traditional inactivated or attenuated virus vaccine. In the meantime, I'm more that willing to test regularly, mask up, avoid crowds indoors, supplement with vitamin D, and maintain a healthy body weight.

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Posted in: Get healthy by heeding the wisdom of the ancients, by embarking on a fast See in context

Dr. David Sinclair recommends intermittent fasting. Fasting has been shown to provide numerous benefits, and studies have shown that fasting for 72 hours can increase autophagy. Anyone interested in the potential health benefits of fasting should google Dr. Valter Longo.

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Posted in: Efforts grow to stamp out use of parasite drug ivermectin for COVID-19 See in context

the drug can be extremely toxic and cause even death

FFS, even water and oxygen can be toxic depending on the dosage. Saying that something is toxic vs something can be toxic is an important distinction.

4 ( +7 / -3 )

Posted in: Efforts grow to stamp out use of parasite drug ivermectin for COVID-19 See in context

Can any of you very briefly actually tell me how an anti-parasitic drug is a remedy for a virus without directing me to an odd website. 

Ivermectin is thought to interfere with the SARS-CoV-2 spike protein binding with a number of key targets, such as SA binding sites on hemoglobin (reducing the chance of clotting) and ACE2 receptors on lung and heart cells (reducing infection). To avoid odd websites, I recommend you try a google scholar search for papers on this topic.

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