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Posted in: Victims' families to sue over fatal 2022 Hokkaido boat accident See in context

The lawyers have also mulled the possibility of suing the state and the Japan Craft Inspection Organization, which conducts inspections for small vessels on behalf of the government, for inadequate inspections of the operator, but they have not made any decision on the matter, they said.

Precisely, the operator acted irresponsibly because those in charge of preventing it were not doing their jobs, it was just a question of time until disaster happened. Until those that are supposed to protect the people from irresponsible operators also suffer consequences for their lack of action disasters like this will keep happening.

0 ( +0 / -0 )

Posted in: Japan enacts law to restrict onshore wind farm construction See in context

even if you believe there is a climate crisis - there isn’t)

On one side the scientific community of the world clearly concluded there is a huge climate crisis and that wind is considered a sustainable, renewable energy source presenting clear and abundant evidence for both conclusions.

On the other side nameless people on the internet say all the scientists of the world are wrong, and their source is "dude, trust me".

It is very simple to understand which side is wrong.

5 ( +6 / -1 )

Posted in: Japan scientists mass-generate cells for sperm, eggs using human iPS See in context

The achievement is important not only in the direct application to reproductive medicine (that would still be years away) but also because the generation of reproductive cells has been considered specially difficult to achieve with efficiency. That this group managed as much as they did in this work means that there is a lot of progress that can be also applied to other kinds of tissue, so it is a huge advancement for regenerative medicine in general.

-1 ( +0 / -1 )

Posted in: Experts say coral reef bleaching near record level globally because of 'crazy' ocean heat See in context

Please tell me how coral reef bleaching is going to hurt mankind and kill people at the end of the day.

Appeals to authority are meaningless without credentials, specially when ignoring well known information that is readily available.

For example

https://www.worldwildlife.org/pages/everything-you-need-to-know-about-coral-bleaching-and-how-we-can-stop-it

Coral bleaching matters because once these corals die, reefs rarely come back. With few corals surviving, they struggle to reproduce, and entire reef ecosystems, on which people and wildlife depend, deteriorate.

What could reasonably be done outside technical progress by education OR euthanizing large part of human population ? 

Again, pretending the repeated appeals from experts about what can realistically be done is not an argument, is trying to excuse not having an argument because of ignorance, which of course only makes the opinion valueless, you do not excuse your position because of lack of knowledge, you only make it clear why it is not valid.

https://davidsuzuki.org/what-you-can-do/top-10-ways-can-stop-climate-change/

https://www.nationalgeographic.com/environment/article/global-warming-solutions

https://www.epa.gov/coral-reefs/what-you-can-do-help-protect-coral-reefs

The position of the scientific organizations that have to do with climate change is clear, and it is not "give up" as you personally choose to do, but instead that action needs to be taken now to limit the damage, obviously the scientific institutions of the whole world are not wrong just because you choose to believe differently.

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Posted in: Sean 'Diddy' Combs apologizes after video shows him assaulting partner See in context

"My behavior on that video is inexcusable," Combs said in a video posted on Instagram, adding he was "disgusted" and "sought out professional help" after the incident including therapy and rehab.

Zero credibility since Combs has previously vehemently denied all accusations against him.

Anybody disgusted of their own actions would begin by accepting them (and the consequences) not pretending nothing happened until a video made that impossible.

5 ( +6 / -1 )

Posted in: Lots of Japanese parents want their kids to work for Nintendo, but not just for the money, survey says See in context

Looking at the previous articles where nintendo took a very strong supporting position for their employees against harassing customers it is understandable that it can enjoy a very positive image as an employer. Specially in the eyes of a generation that have had to endure a lot of insecurities and interpersonal problems at work.

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Posted in: Experts say coral reef bleaching near record level globally because of 'crazy' ocean heat See in context

This wouldn't be happening without climate change. 

It is difficult to find something so definitively related to the damage, yet unscrupulous people will still insist there is nothing to worry about it, or that humans had nothing to do with it since it is a "natural process", at some point irrational antiscientific claims work more to discredit those that choose to repeat them than to support what is being said.

-1 ( +5 / -6 )

Posted in: Will AI replace doctors who read X-rays, or just make them better than ever? See in context

In the near term, experts say AI will work like autopilot systems on planes — performing important navigation functions, but always under the supervision of a human pilot.

The article makes much better explained points but at the end the result is what is being repeated elsewhere, it is irrational to expect AI to be able to replace professionals at this point. No matter how useful a tool is, as long as the professional is required to be there to use it then it remains only that, a tool. For all the people that baselessly claim radiologists have been already replaced, the reality is as this article helpfully describes, AI represent tools, limited in scope to be useful.

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Posted in: Attacking birth control pills, U.S. influencers push misinformation See in context

Let information be free, regardless if it is true or false. 

Criminals of all types would readily support this, but part of the positive consequences of social progress is that we now understand that letting people fool and mislead others for personal profit is not something worth protecting. The false dichotomy of "everything should be allowed or else nothing would be allowed" is of course obviously invalid, when people choose to lie in order to take advantage of others they should be made responsible for their actions and punished.

-2 ( +4 / -6 )

Posted in: Measures are needed to accommodate people who are suffering from long-COVID, such as proposing flexible work styles in accordance with their symptoms. See in context

Social and traditional media outlets are allowing people to spread disinformation about long covid including calling sufferers fakers, the links are about articles describing the problem happening in a general sense.

The same outlets also let people spread disinformation about vaccines and treatments, are you also trying to say you have seen no examples of this? for example promoting risky useless treatments like ivermectin or saying the vaccine facilitates the appearance of escape mutants? because those are also examples of false/misleading information that that professionals in public health consider put people at risk, these comments are present only few outlets that allow them but they are definitely possible to find.

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Posted in: Measures are needed to accommodate people who are suffering from long-COVID, such as proposing flexible work styles in accordance with their symptoms. See in context

OK, so perhaps you could provide some examples of people saying they are faking it

It is not even difficult to see how these disinformation efforts are being conducted.

https://www.reuters.com/article/idUSL1N2S728P/

https://philanthropynewsdigest.org/news/other-sources/article/?id=14711088

https://www.ualberta.ca/folio/2023/01/covid-long-haulers-face-stigma-lingering-symptoms.html

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01121-2/fulltext

When something is so easily corroborated the argument that you have not seen it helps demonstrating more a personal bias about rejecting information that is readily available, not that there is no information.

We're talking about "long COVID", and according to Queensland's chief health officer their research found COVID post-viral syndrome indistinguishable from seasonal influenza and other respiratory illnesses one year after infection.

And again this "research" do not present the minimum amount and quality of data to actually support those conclusions against the mountains of evidence that have been presented by the best specialists of the world, in multiple countries. The conclusions that the risk of long covid is not different from what is observed from other diseases is not supported by the information they present. Once again to contradict a consensus so well stablished (the specially important risk) requires much stronger evidence.

0 ( +2 / -2 )

Posted in: Attacking birth control pills, U.S. influencers push misinformation See in context

No, because as you stated, "It does not make sense".

Not only stated, but demonstrated it with arguments, arguments that you could not even address, much less refute.

It makes sense to everyone else though.

Well, you could not even argue how it could make sense to claim people offering options are supposedly trying to control people, that demonstrate the opposite, it is still a nonsensical claim.

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Posted in: Shionogi says COVID treatment did not meet endpoint in late-stage trial See in context

Yeah, just enough to place some selection pressure to mutate

Which would still happen without the vaccine, except that vaccinated people will control the infection sooner therefore making the appearance of escape mutants a much less likely possibility, which again is exactly what happened as observed by variants of interest appearing in populations with low vaccinations rates.

but not enough to prevent or slow down infection or replication

Yes, slow down infection and replication, the comparison is again against uninfected patients, that have zero reduction, so any reduction due to vaccination is still an advantage, this is not that difficult to understand.

Natural immunity targets much more than just the spike protein

Which makes it irrelevant when it still lets scape mutants appear with higher probability, which (again) is exactly what happened and why Geert Vanden Bossche was humiliated when his predictions turned up being completely wrong and the variants appeared in populations not yet vaccinated.

The problem is that you are trying to misrepresent neutralizing antigenic regions as if the immunity gained from infection did not target exactly the same regions, that is false, escape mutants appeared on unvaccinated populations precisely because immunity gained from infection facilitate changes in the same regions, just giving the virus much more opportunities to survive and be transmitted to other people.

-1 ( +1 / -2 )

Posted in: Attacking birth control pills, U.S. influencers push misinformation See in context

As you acknowledge your misunderstanding by saying it does not make sense, that proves more for the opposite view.

The opposite, the one recognizing a misunderstanding would be you that were unable to even argument, my position is clear and valid, giving control is not congruent with the accusation of trying to be in control, therefore the accusation is nonsensical and safe to disregard. No argument against it? that means you are recognizing thinking otherwise is wrong.

-2 ( +4 / -6 )

Posted in: Attacking birth control pills, U.S. influencers push misinformation See in context

It not make sense it is the truth.

It does not make sense as the arguments readily proved, arguments against which you could not do anything against, and being nonsensical it is clear it is not true.

In order to say this is not so you would require to argue, specifically how those that want to give options to the people are supposedly trying to control the people by doing so, if you can't then the only logical option is to accept it makes no sense.

2 ( +10 / -8 )

Posted in: Attacking birth control pills, U.S. influencers push misinformation See in context

It's disturbing the way conservatives are infiltrating the "wellness" industry to push their agenda

But hardly surprising, when a significant portion of the people on both groups share a systematic rejection of scientific conclusions for personal profit it is natural for them to mix and share objectives.

But liberals want to overall control the nation

That makes absolutely no sense, if one side is about giving options and the other is about taking them away (or misleading people into rejecting safe and effective options) the argument of "control" can only be used validly against the second group. It is as easy as finding out which one has the support of the scientific experts on the field, be it reproductive rights, climate change, the pandemic, etc.

-2 ( +8 / -10 )

Posted in: Shionogi says COVID treatment did not meet endpoint in late-stage trial See in context

It was proposed by Geert Vanden Bossche, a leading vaccination expert.

And disproved by the evidence collected in the world, that is the whole point of science, that evidence can prove anybody is wrong, if the person disproved fails to act professionally and insist on disproved theories that rely on deeply flawed understanding of immunology that on that person, it does nothing to disprove the consensus.

 Plus, it makes perfect sense to anyone with any understanding of immunology

No it does not, not even a single organization related to immunology says this makes any sense, only discredited people that have been demonstrated wrong with scientific arguments. There is no point in pretending every medical association of immunology does not understand the field, it is beyond irrational.

Note that the variants are highly mutated in the area targeted by the vaccine....

And the area targeted by natural immunity as well, that is the point of all adaptive immunity and escape mutants, this is like being surprised that survivors of violence have injuries in non-lethal organs.

That might be true if immunity was achieved immediately after injection

No it does not, a vaccine recieved 1 hour before the infection means the person have one hour of advantage producing immunity (in reality much more since replication takes much longer than the stimulus from vaccines) that is just another serious misunderstanding of how immunity works, The comparison is not between a person in the middle of producing immunity and someone that coursed by the full infection but between that incomplete adaptive immunity and someone that has none of it. 1% of immunity because of vaccines means 1% more than the person that has just been infected.

That is again why there was no surprise in finding variants of importance appearing in poorly vaccinated populations, to the great shame of Vanden Bossche that predicted the opposite would happen, and ended up being totally wrong.

-1 ( +1 / -2 )

Posted in: Measures are needed to accommodate people who are suffering from long-COVID, such as proposing flexible work styles in accordance with their symptoms. See in context

Strange, I've never read or heard anyone saying they were just faking it.

Willful ignorance do not refute the systematic downplaying antiscientific propaganda have done for sufferers of long covid, even trying to misrepresent the acute infection as if it was not specially risky compared with other infection.

I have however heard many wondering why they was so much mention in the MSM about long COVID, but no mention about vaccine injury

Because the first is a serious and growing public health problem and the second is a tiny minuscule thing in comparison, there is no real issue to address with the vaccines, that is also another of the disinformation efforts that media is allowing and that puts in risk the health of the population.

Also, according to Queensland's chief health officer, they should stop using the term "long COVID", because according to their research they found COVID post-viral syndrome indistinguishable from seasonal influenza and other respiratory illnesses one year after infection.

But since he presented no evidence (nor even an effort to discuss scientifically) the evidence presented by many actual authorities in the field around the world that prove covid have specially important risks that affect the health in the long term (or even permanently) there is no real weight on this declaration. A representative of a local hospital saying there is no cancer would be comparable.

0 ( +2 / -2 )

Posted in: Measures are needed to accommodate people who are suffering from long-COVID, such as proposing flexible work styles in accordance with their symptoms. See in context

Social and traditional media should assume part of the responsibility for this situation, allowing people to spread disinformation about the long lasting consequences of covid makes it easier for people in general to disregard those consequences as unimportant and the sufferers as if they were complaining about nothing. For every article about how dangerous and crippling covid can be on the long term there are dozens of people trying to convince others that this is false and people are just faking.

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Posted in: Eisai starts rolling submission for injectable version of Alzheimer's drug with FDA See in context

The US system might be difficult to people who are not working in the field but on the bright side, the FDA continues to back drugs such as this, and the result is only a positive one for society.

Saying it is difficult to understand do not excuse making claims that are not correct, you can search all the information that the FDA produces constantly, they do not claim to help or support the development of drugs, that claim is still false.

-3 ( +1 / -4 )

Posted in: Low-cost MRI paired with AI produces high-quality results See in context

Yes, AI has already replaced humans in the healthcare industry, such as in France,

And the US.

Since you were completely unable to support this claim even after it was specifically debunked as baseless you are recognizing exactly that, something that can safely be ignored because it is not happening. AI can at much provide limited tools, never replace professionals in the healthcare industry.

This article explicitly says so, the new technology may (if validated) replace more expensive MRI machines, but it would be false to claim it could replace the radiologist, that would make no sense.

-2 ( +1 / -3 )

Posted in: Hotter, drier, sicker? How a changing planet drives disease See in context

Are they kidding? Try to exist a few hours in the Arctic where it is surely not hot and dry, and after that we discuss your new and assumed much better health condition, if there still are some left.

What has this to do with the infectious diseases that the article is talking about? Is your belief that infections are rampant in the Arctic?

2 ( +10 / -8 )

Posted in: Eisai starts rolling submission for injectable version of Alzheimer's drug with FDA See in context

Leqembi is still too expensive, risky and have very limited efficacy, but it is still better than nothing so an easier method for delivery means extra benefit for the patients. With any luck better treatments will appear before it is adopted more generally.

This is good news if these drugs receive FDA backing.

This is a mistake already corrected several times, the FDA do not back any drug, the laboratories do all the work by themselves to develop and test them and the FDA is only involved in approving them (or not).

Not even the FDA makes this claim of "backing" any drugs, it should be clear they would know their own role better than anybody else.

-5 ( +2 / -7 )

Posted in: Shionogi says COVID treatment did not meet endpoint in late-stage trial See in context

No, actually WP is spot on. And this was predicted by Geert Vanden Bossche who warned us about mass vaccination during a pandemic, and he has an advanced understanding of immunology.

Geert Vanden Bossche never provided any data to support this claim, and could not even refute the mountains of data and scientific arguments that proved the claim was wrong and false, based only on a terribly bad misunderstanding of how immunity works, that means the claim is still demonstrated false. Easy to prove the moment the variants of importance that appeared when only some countries had good vaccination efforts did so on poorly vaccinated populations, exactly the opposite of what would be expected if the vaccines facilitated this.

By mass vaccinating during a pandemic you are encouraging the emergence of escape mutants through mutations in the area targeted by the vaccines

That is of course false, any immunity means an advantage, so unvaccinated people leave more time for the virus to mutate and adapt compared with anybody that have even partial immunity. Escape mutants are positively correlated with lower levels of adaptive immunity, which completely corresponds with what was observed with delta, omicron, etc.

-1 ( +1 / -2 )

Posted in: Low-cost MRI paired with AI produces high-quality results See in context

No, AI is not replacing professionals in the health care industry, at much it provides better tools for those professionals to do their jobs, since you have never been able to bring any source of the claim of this happening in France it is clear this claim can be discarded as unsupported.

-2 ( +1 / -3 )

Posted in: Hotter, drier, sicker? How a changing planet drives disease See in context

In tropical climates, warmer, wetter weather is driving an explosion in dengue fever.

People in countries like Japan can make the mistake of feeling this is something that only happens far away, but vector borne diseases can be just one airplane away. Every year mosquitoes with Dengue and other viral infections are found around Narita and Haneda airports, and some years even small outbreaks are identified already, the only thing that stops those small outbreaks from becoming a disaster is a winter that the infected mosquitoes can't survive, the moment mosquitoes can over-winter the outbreaks will begin at the same time as the mosquito season, cities like Tokyo are completely unprepared to deal with the huge number of patients that this would cause.

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Posted in: Shionogi says COVID treatment did not meet endpoint in late-stage trial See in context

That's right, the vaccines promoted the appearance of variants.

No they did not, that is a completely mistaken idea born from not understanding basic immunology, vaccines reduce the risk of variants of importance appearing, that has been known for years already.

-1 ( +1 / -2 )

Posted in: Shionogi says COVID treatment did not meet endpoint in late-stage trial See in context

Yes, such honesty in a pharma company is extremely unusual.

No, it is not, specially with the strict controls and rules in place, enough so that when this is not the case it is reported in the news precisely as the exception. The ever ongoing confirmation that comes from the continuous collection of evidence makes dishonesty a losing proposition from the very beginning.

Nah, it was widely acknowledged to be a milder virus, even among the unvaccinated who did not take any of those "good treatments".

Trying to dismiss the effect on the community from vaccination as if it didn't exist is what refutes that as an argument. For any infection for which the inoculum affects the clinical presentation a vaccine that reduces the exposure in general means it also has an effect reducing the burden of the infection in general as well, vaccines and better treatments are recognized as a very important factor that reduced the risks from covid (that are still important to this day).

Failed repurposed drugs like ivermectin on the other hand offered no benefit no matter which variant of the virus they were used against.

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Posted in: Shionogi says COVID treatment did not meet endpoint in late-stage trial See in context

So the pill didn't work, the jab experiment certainly didn't work. At least Big Pharma are happy.

Other drugs work without problems, the vaccines are considered by the medical community a huge success that saved millions of lives. The people interested in public health are happy, only the antiscientific antivaxxer groups ended up very unhappy when their conspiracy theories were so completely disproved.

Neither did the Vaccines but supposedly they reduced symptoms

The vaccines greatly surpassed the expected efficacy and safety standards, which were then confirmed when used in the population, being irrationally in denial of the opinion of the medical community of the world do not make their conclusions wrong.

A problem with Covid drug trials carried out later in the pandemic (e.g. this one and IVERMILCO study) is that they were done at a time when the virus was much milder.

In great part thanks to vaccination, and also because good treatments are already available, coming out late in the development race meant Shionogi had to greatly surpass the predecessors, it was not a surprise this did not happen, the Japanese government shares some of the responsibility because of the way it makes unnecessarily complicated to develop new therapeutic interventions (and refrain from using those that he already have access to).

i still did not find news from Astra Zeneca here and their retreat from covid "business"...?

Links were made available before, about how the AZ vaccine is considered by the experts a very successful enterprise that saved uncountable lives, just not as good as other options available, which is why it makes no sense to keep trying to sell it.

For me this is refreshing.

Props to Shionogi for taking the honest route!

For good or for bad this is less about a company being honest and more about the regulations and controls already in place making that company unable to get away with a product that is worse than what is already available.

-1 ( +3 / -4 )

Posted in: Brazil's catastrophic weather spawns spate of conspiracy theories See in context

Unfortunately in some parts of the world scientific literacy is going backwards, and when a clear well proved source for disasters is found people with low (or no) understanding of the science will instead turn into conspiracies and irrational denial to excuse not assuming their responsibility, it will never be that they support politicians that make climate change worse, the answer must be that impossible conspiracy they choose to believe. Further complicated by the negative, antisocial personalities of the same people, making them repeat things they themselves understand are false.

4 ( +7 / -3 )

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